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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1747825Generated: October 25, 2026

Potassium Carbonate → 5-ethynyl-1-phenyl-1H-pyrazole

https://huagongshe.com/reaction/1747825

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant1-phenyl-5-[(trimethylsilyl)ethynyl]-1H-pyrazoleHCID 89586259—
SolventMethanolHCID 887—
Product5-ethynyl-1-phenyl-1H-pyrazoleHCID 8958633685.7%

Reaction Steps

To a solution of 1-phenyl-5-[(trimethylsilyl)ethynyl]-1H-pyrazole (1.20 g) in methanol (20.0 mL) was added potassium carbonate (0.173 g), and the mixture was stirred at room temperature for 3 hr. The reaction mixture was filtered, and the filtrate was concentrated to give the title compound (0.72 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150588B2
Source datasetuspto-grants-2015_10
ORD IDord-5dff2df3a38046b884dfbd759bd3216a
Source noteuspto-grants-2015_10