HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 5-ethynyl-1-phenyl-1H-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-phenyl-5-[(trimethylsilyl)ethynyl]-1H-pyrazole | HCID 89586259 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-ethynyl-1-phenyl-1H-pyrazole | HCID 89586336 | 85.7% |
Reaction Steps
To a solution of 1-phenyl-5-[(trimethylsilyl)ethynyl]-1H-pyrazole (1.20 g) in methanol (20.0 mL) was added potassium carbonate (0.173 g), and the mixture was stirred at room temperature for 3 hr. The reaction mixture was filtered, and the filtrate was concentrated to give the title compound (0.72 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150588B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-5dff2df3a38046b884dfbd759bd3216a |
| Source note | uspto-grants-2015_10 |