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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 174790Generated: October 27, 2026

Hydrochloric Acid → 3-Chloro-N-[2-(dimethylamino)ethyl]-2-fluoro-N-methylisonicotinamide

https://huagongshe.com/reaction/174790

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantChloroformHCID 6212—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1,2-Ethanediamine, N1,N1,N2-trimethyl-HCID 67338—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant3-Chloro-2-fluoropyridine-4-carboxylic acidHCID 12175428—
Product3-Chloro-N-[2-(dimethylamino)ethyl]-2-fluoro-N-methylisonicotinamideHCID 68429843—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-698d6be99aa741608af7c32e16854ee0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)