Formic Acid → HCID 67776661, compound

HRID 1748141Notes

Reaction equation

HRID 1748141 reaction equation
[CH:1]([C:3]1[CH:4]=[CH:5][C:6]([C:9]#[N:10])=[N:7][CH:8]=1)=[CH2:2].CO.[CH:13](OC=O)=O.C(O)=O.[NH2:21][NH2:22]>>[NH:21]1[C:9]([C:6]2[CH:5]=[CH:4][C:3]([CH:1]=[CH2:2])=[CH:8][N:7]=2)=[N:10][CH:13]=[N:22]1

Participants

6

Reactant 5

HCID 284Formic AcidHCID 887MethanolHCID 9321HydrazineHCID 9548680Formic anhydrideHCID 152194325-Ethenylpyridine-2-carbonitrile

Product 1

HCID 67776661HCID 67776661, compound

Procedure

5-vinylpicolinimidohydrazine (4-1) was synthesized by adding the 5-vinylpicolinonitrile intermediate (1-2) to a methanol solution, in which hydrazine was dissolved, and reacted at 24° C. 2-(1H-1,2,4-triazol-5-yl)-5-vinylpyridine (4-2) was prepared by reacting the 5-vinylpicolinimidohydrazine (4-1) with a mixed solution of formic anhydride and formic acid (in a volume ratio of 1:1).

Workup

  1. customreacted at 24° C

Sources & evidence

ORD record
ord-27d092000a7c4bfc9e9d837f37151c0a
Source dataset
uspto-grants-2015_10
Patent number
US09150601B2

Reaction notes

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