HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyclopropyl-3-Oxopropionic Acid Methyl Ester → 5-Cyclopropyl-3-(4,4-dimethylcyclohexyl)isoxazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyclopropyl-3-Oxopropionic Acid Methyl Ester | HCID 10130016 | — |
| Reactant | N-Hydroxy-4,4-dimethylcyclohexanecarbimidoyl chloride | HCID 86704402 | — |
| Product | 5-Cyclopropyl-3-(4,4-dimethylcyclohexyl)isoxazole-4-carboxylic acid | HCID 67983815 | — |
Reaction Steps
5-cyclopropyl-3-(4,4-dimethylcyclohexyl)isoxazole-4-carboxylic acid (I-9E) Was prepared by reaction of N-hydroxy-4,4-dimethylcyclohexanecarbimidoyl chloride and methyl 3-cyclopropyl-3-oxopropanoate following the same protocol as described for I-6E. MS m/z 264.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150568B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-9af996ffa3ee428aaffeb590dd090040 |
| Source note | uspto-grants-2015_10 |