Aluminium lithium hydride → HCID 67983881, compound

Participants

Reaction Steps

(5-cyclopropyl-3-(4,4-dimethylcyclohexyl)isoxazol-4-yl)methanol (I-9F) was prepared by reaction of methyl 5-cyclopropyl-3-(4,4-dimethylcyclohexyl)isoxazole-4-carboxylate and LiAlH4 following the same protocol as described for I-6F. 1H NMR (400 MHz, CDCl3) δ 4.56 (s, 3H), 2.65 (m, 1H), 2.05-1.99 (m, 1H), 1.81-1.75 (m, 4H), 1.52-1.48 (m, 2H), 1.33-1.28 (m, 2H), 1.14-1.10 (m, 2H), 1.04-1.01 (m, 2H), 0.95 (s, 3H), 0.94 (s, 3H). MS m/z 250.1 (M+1).

Provenance & Evidence