Potassium Cation → tert-butyl N-[1-amino-3-[4-(4-cyanophenyl)phenyl]-1-oxopropan-2-yl]carbamate

HRID 174823Notes

Reaction equation

HRID 174823 reaction equation
[C:21](#[N:22])[c:23]1[cH:24][cH:25][c:26]([B:29]([OH:30])[OH:31])[cH:27][cH:28]1.[C:32](=[O:33])([O-:34])[O-:35].[K+:36].[K+:37].[NH2:1][C:2]([CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8]([I:11])[cH:9][cH:10]1)[NH:12][C:13]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])=[O:20].[O:38]1[CH2:39][CH2:40][O:41][CH2:42][CH2:43]1>>[NH2:1][C:2]([CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8](-[c:26]2[cH:25][cH:24][c:23]([C:21]#[N:22])[cH:28][cH:27]2)[cH:9][cH:10]1)[NH:12][C:13]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])=[O:20]

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 27343264-Cyanophenylboronic acidHCID 67515529S-[1-Carbamoyl-2-(4-iodo-phenyl)-ethyl]-carbamic acid tert-butyl ester

Product 1

HCID 72328342tert-butyl N-[1-amino-3-[4-(4-cyanophenyl)phenyl]-1-oxopropan-2-yl]carbamate

Sources & evidence

ORD record
ord-f09577bd20cb4643ba913b911b96af3e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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