Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 4-Methyl-3-nitrobenzoic acid | HCID 7319 | — |
| Product | Ethyl 4-methyl-3-nitrobenzoate | HCID 14945864 | 98% |
Reaction Steps
4-Methyl-3-nitrobenzoic acid (71 g, 0.39 mol) is dissolved in dry ethanol (600 mL) and dry HCl gas is bubbled into the solution for 5 min. The reaction mixture is heated to 90° C. under N2 for 20 h. The solvent is removed under vacuum to afford the title compound as a straw-colored liquid (80.0 g, 98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09150577B2 |
|---|
| Source dataset | uspto-grants-2015_10 |
|---|
| ORD ID | ord-9f654e6662ee46b1b7701f0891132f94 |
|---|
| Source note | uspto-grants-2015_10 |
|---|
