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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1748251Generated: October 31, 2026

(2R)-1-aminopropan-2-ol → (4S)-4-methyl-1-oxo-1,2,3,4-tetrahydropyrazino[1,2-a]indole-7-carboxylic acid

https://huagongshe.com/reaction/1748251

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R)-1-aminopropan-2-olHCID 439938—
Reactant(4R)-4-methyl-1-oxo-1,2,3,4-tetrahydropyrazino[1,2-a]indole-7-carboxylic acidHCID 67235445—
Product(4S)-4-methyl-1-oxo-1,2,3,4-tetrahydropyrazino[1,2-a]indole-7-carboxylic acidHCID 67238141—

Reaction Steps

This compound is synthesized using the similar procedure used to prepare (4R)-4-methyl-1-oxo-1,2,3,4-tetrahydropyrazino[1,2-a]indole-7-carboxylic acid (Intermediate C), replacing (2S)-1-aminopropan-2-ol with (2R)-1-aminopropan-2-ol in Step 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09150577B2
Source datasetuspto-grants-2015_10
ORD IDord-9a2c533d4bb840f6a1f0ae857aec03b6
Source noteuspto-grants-2015_10