Ammonium formate → 1-N-(propan-2-yl)benzene-1,2-diamine

Participants

Reaction Steps

To a solution of 2-nitro-N-(propan-2-yl)aniline (828 mg, 4.6 mmol) in ethanol (10 mL) under a nitrogen atmosphere is carefully 20% palladium on carbon (50 mg, Degussa type) followed by ammonium formate (1.4 g, 23 mmol) and the reaction is stirred overnight. The suspension is carefully filtered through a bed of Celite and the filtrate is rinsed with additional ethanol (10 mL). The filtrate is concentrated and the residue is partitioned between water and ethyl acetate. The organic layer is dried (Na2SO4) and concentrated.

Provenance & Evidence