HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 1-(5-bromopyridin-2-yl)-5-methylpyrazole-4-carboxylate → 1-(5-Ethyl-6-methylpyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 1-(5-bromopyridin-2-yl)-5-methylpyrazole-4-carboxylate | HCID 46739344 | — |
| Reactant | 1-(5-Iodo-6-methylpyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid ethyl ester | HCID 86692414 | — |
| Product | 1-(5-Ethyl-6-methylpyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid | HCID 86692420 | — |
Reaction Steps
1-(5-Iodo-6-methylpyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid ethyl ester described n Reference Example 31 was used in place of 1-(5-bromopyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid ethyl ester in Reference Example 28, and reacted and treated in a similar manner to give the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09150555B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-bf5a7cd68f734a0289ea6c9a5d43d1d3 |
| Source note | uspto-grants-2015_10 |