4-[4-(5-Bromo-3-methylpyridin-2-yl)cyclohex-3-en-1-yl]morpholine → 6-(4-{[tert-Butyl(dimethyl)silyl]oxy}cyclohex-1-en-1-yl)-5-methylpyridin-3-amine

Participants

Reaction Steps

5-Bromo-2-(4-{[tert-butyl(dimethyl) silyl]oxy}cyclohex-1-en-1-yl)-3-methylpyridine (8.4 g) was used inn place of 4-[4-(5-bromo-3-methylpyridin-2-yl)cyclohex-3-en-1-yl]morpholine in Reference Example 108, and reacted and treated in a similar manner to give the titled compound (5.76 g) as a brown solid.

Provenance & Evidence