HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1748653Generated: October 31, 2026
1,2-Dichlorobenzene → HCID 86692592, compound
https://huagongshe.com/reaction/1748653
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,2-Dichlorobenzene | HCID 7239 | — |
| Reactant | Succinic anhydride | HCID 7922 | — |
| Reactant | HCID 72700119 | HCID 72700119 | — |
| Catalyst | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 86692592 | HCID 86692592 | 40.7% |
Reaction Steps
1-(4-Chlorophenyl)-N-[6-(1-cyano-4-hydroxycyclohexyl)pyridin-3-yl]-5-methyl-1H-pyrazole-4-carboxamide (0.42 g), succinic anhydride (0.11 g) and p-toluenesulfonic acid hydrate (5 mg) were added to 1,2-dichlorobenzene (4 ml) and stirred at 150° C. for seven hours. The reaction solution was treated with water and the precipitated solid was recrystallized from aqueous isopropanol to give the titled compound (0.21 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09150555B2 |
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| Source dataset | uspto-grants-2015_10 |
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| ORD ID | ord-0894c1a79ff1417bb6cdc394c8d2f75a |
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| Source note | uspto-grants-2015_10 |
|---|
