4-Nitroaniline → HCID 15044295, compound

Participants

Reaction Steps

4-Nitroaniline (6.9 g, 0.05 mol) is suspended in water (150 ml) and 35% HCl (17.3 g) is added. To this is added a solution of sodium nitrite (3.6 g, 0.053 mol) at 0-5° C., pH<1. Once all solid has dissolved, excess nitrous acid is destroyed by addition of sulfamic acid and the solution is then added dropwise to a solution of 2,5-diethoxyaniline (9.4 g, 0.052 mol) in water (300 ml) and 35% HCl

Provenance & Evidence