HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-(trifluoromethyl)benzenethiol → 2-Methyl-2-(4-(5-(trifluoromethyl)benzo[d]thiazol-2-yl)phenoxy)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-(trifluoromethyl)benzenethiol | HCID 88042 | — |
| Reactant | Ethyl 2-(4-formylphenoxy)-2-methylpropanoic acid | HCID 86709921 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Methyl-2-(4-(5-(trifluoromethyl)benzo[d]thiazol-2-yl)phenoxy)propanoic acid | HCID 68279297 | — |
Reaction Steps
A solution including Compound 97c (1.0 eq.) and 2-amino-4-trifluoromethylbenzenethiol (1.0 eq.) was stirred in a methanol solvent at room temperature. After methanol was removed, the precipitate was filtered, and washed with cold methanol to obtain a solid target product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09155690B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-10ea578614bc4bc79362ceb027137c04 |
| Source note | uspto-grants-2015_10 |