Ethyl Acrylate → HCID 89843276, compound

Participants

Reaction Steps

The target solid of step 1 (4 g, 14.78 mmol), Herrmann's palladacycle (0.277 g, 0.30 mmol), and [(t-Bu)3Ph]BF4 (0.171 g, 0.60 mmol) mixed in DMF (40 mL) was added with ethyl acrylate (1.58 mL, 14.76 mmol) and Cy2NMe (3.27 mL, 14.78 mmol) and irradiated with microwave at 150° C. for 30 min (two times). The resulting mixture was evaporated to get dark green residue. The residue was suspended in ethyl acetate (50 mL) and washed with water (3×50 mL). The organic layer dried over MgSO4 was evaporated to get crude yellow solid of target compound of step 2. The yellow solid was put to step 3 without further purification.

Provenance & Evidence