HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-(((tert-butoxy)carbonyl)(methyl)amino)propanoic acid → tert-Butyl methylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-(((tert-butoxy)carbonyl)(methyl)amino)propanoic acid | HCID 7009590 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | tert-Butyl methylcarbamate | HCID 527635 | — |
Reaction Steps
The product from Step 1 was coupled with Boc-N-methyl-L-alanine according to General procedure 4 (but using dimethyl formamide instead of dichloromethane) to afford (S)-1-(6-cyano-5-nitro-pyridin-2-ylcarbamoyl)-ethyl]-methyl-carbamic acid tert-butyl ester. MS: [M−H]−=348.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09155743B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-16f010eceb224ce6b14c74021129279e |
| Source note | uspto-grants-2015_10 |