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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1749301Generated: October 25, 2026

1-cyclopentyl-N-methylpiperidin-4-amine → 2-(5-amino-4,6-dimethylpyrimidine-2-yloxy)-N-(1-(cyclopentyl)piperidine-4-yl)-N-methylacetamide

https://huagongshe.com/reaction/1749301

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-cyclopentyl-N-methylpiperidin-4-amineHCID 43315369—
Reactant2-(5-(Tert-butoxycarbonylamino)-4,6-dimethylpyrimidine-2-yloxy)acetic acidHCID 59336168—
Product2-(5-amino-4,6-dimethylpyrimidine-2-yloxy)-N-(1-(cyclopentyl)piperidine-4-yl)-N-methylacetamideHCID 59336200—

Reaction Steps

The title compound was synthesized from Compound 9 and 1-cyclopentyl-N-methylpiperidine-4-amine in the same manner as in Example 64.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09156817B2
Source datasetuspto-grants-2015_10
ORD IDord-43fb082d487d47a08fa978a6d3d84532
Source noteuspto-grants-2015_10