2-(5-(Tert-butoxycarbonylamino)-4,6-dimethylpyrimidine-2-yloxy)acetic acid → HCID 59336116, compound

HRID 1749303Notes

Reaction equation

HRID 1749303 reaction equation
C(OC([NH:8][C:9]1[C:10]([CH3:21])=[N:11][C:12]([O:16][CH2:17][C:18]([OH:20])=O)=[N:13][C:14]=1[CH3:15])=O)(C)(C)C.[CH:22]1([C:26]([N:28]2[CH2:33][CH2:32][CH:31]([NH:34][CH3:35])[CH2:30][CH2:29]2)=[O:27])[CH2:25][CH2:24][CH2:23]1>>[NH2:8][C:9]1[C:14]([CH3:15])=[N:13][C:12]([O:16][CH2:17][C:18]([N:34]([CH:31]2[CH2:32][CH2:33][N:28]([C:26]([CH:22]3[CH2:25][CH2:24][CH2:23]3)=[O:27])[CH2:29][CH2:30]2)[CH3:35])=[O:20])=[N:11][C:10]=1[CH3:21]

Participants

3

Reactant 2

HCID 593361682-(5-(Tert-butoxycarbonylamino)-4,6-dimethylpyrimidine-2-yloxy)acetic acidHCID 60820117HCID 60820117, compound

Product 1

HCID 59336116HCID 59336116, compound

Procedure

The title compound was synthesized from Compound 9 and cyclobutyl (4-(methylamino)piperidine-1-yl)methanone in the same manner as in Example 64.

Sources & evidence

ORD record
ord-970d0e65f2974d5ab00352bcdde5bbb8
Source dataset
uspto-grants-2015_10
Patent number
US09156817B2

Reaction notes

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