HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,5-dimethyl-1H-pyrazol-4-amine → 4-Bromo-2,6-dichloro-N-(1,5-dimethyl-1H-pyrazol-4-yl)-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,5-dimethyl-1H-pyrazol-4-amine | HCID 573813 | — |
| Reactant | 4-Bromo-2,6-dichlorobenzene-1-sulfonyl chloride | HCID 2737466 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 4-Bromo-2,6-dichloro-N-(1,5-dimethyl-1H-pyrazol-4-yl)-benzenesulfonamide | HCID 58561405 | 64.3% |
Reaction Steps
Prepared from 4-bromo-2,6-dichlorobenzenesulfonyl chloride (500 mg, 1.54 mmol) and 4-amino-1,5-dimethyl-1H-pyrazole (172 mg, 1.55 mmol) in pyridine (3 ml) according to the method of intermediate 1, to give the title compound as a cream solid (392 mg, 0.99 mmol, 64%). δH (D-6 DMSO, 300K) 9.91 (1H, s), 7.97 (2H, s), 3.64 (3H, s), 2.04 (3H, s). m/z (ES+, 70V) 399.9 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09156811B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-a95dfe19bb7846d89faa480e860fd947 |
| Source note | uspto-grants-2015_10 |