HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Methanesulfonyl)-2,3-dihydro-1H-indole → 5-(Methylsulfonyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Methanesulfonyl)-2,3-dihydro-1H-indole | HCID 2736136 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 5-(Methylsulfonyl)-1H-indole | HCID 14973230 | 71.6% |
Reaction Steps
A solution of 5-(methylsulfonyl)indoline (0.213 g, 1.08 mmol) in chloroform (4 mL) was added with manganese dioxide (0.939 g, 10.8 mmol), and the mixture was stirred at room temperature for 9 hours. The reaction mixture was filtered through Celite, and the resulting filtrate was concentrated to obtain 5-(methylsulfonyl)-1H-indole (0.151 g, 71%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09156827B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-1b8962c90d08464d995d6db8721b1993 |
| Source note | uspto-grants-2015_10 |