Methanol → (2R,4S)-tert-butyl 4-((tert-butyldimethylsilyl)oxy)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
Reaction equation
[BH4-:1].[C:3](=[O:4])([O:5][C:6]([CH3:7])([CH3:8])[CH3:9])[N:10]1[CH:11]([CH:12]=[O:13])[CH2:14][CH:15]([O:17][Si:18]([CH3:19])([CH3:20])[C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16]1.[CH3:25][OH:26].[Na+:2]>>[C:3](=[O:4])([O:5][C:6]([CH3:7])([CH3:8])[CH3:9])[N:10]1[CH:11]([CH2:12][OH:13])[CH2:14][CH:15]([O:17][Si:18]([CH3:19])([CH3:20])[C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16]1Participants
5
Sources & evidence
- ORD record
- ord-1778bbc29d4b4d2db6bd6bbbab28fcdd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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