6-Chloro-2-(piperazin-1-yl)-1,3-benzothiazole → HCID 67609578, compound

HRID 1750032Notes

Reaction equation

HRID 1750032 reaction equation
[Cl:1][C:2]1[CH:16]=[CH:15][C:5]2[N:6]=[C:7]([N:9]3[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]3)[S:8][C:4]=2[CH:3]=1.[N:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[S:23]([NH:26][C:27]1[CH:28]=[C:29]([CH:33]=[CH:34][CH:35]=1)[C:30](O)=[O:31])(=[O:25])=[O:24]>>[Cl:1][C:2]1[CH:16]=[CH:15][C:5]2[N:6]=[C:7]([N:9]3[CH2:14][CH2:13][N:12]([C:30]([C:29]4[CH:28]=[C:27]([NH:26][S:23]([C:18]5[CH:19]=[CH:20][CH:21]=[CH:22][N:17]=5)(=[O:24])=[O:25])[CH:35]=[CH:34][CH:33]=4)=[O:31])[CH2:11][CH2:10]3)[S:8][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 27465956-Chloro-2-(piperazin-1-yl)-1,3-benzothiazoleHCID 676093003-(Pyridine-2-sulfonamido)benzoic acid

Product 1

HCID 67609578HCID 67609578, compound

Procedure

Compound 11 is prepared using synthesis method 2 using intermediates 3g and 5a (yield: 60%)

Sources & evidence

ORD record
ord-2d2594f7563847339d93dc07be9cfe7d
Source dataset
uspto-grants-2015_10
Patent number
US09156834B2

Reaction notes

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