6-Chloro-2-(piperazin-1-yl)-1,3-benzothiazole → HCID 67607460, compound

HRID 1750033Notes

Reaction equation

HRID 1750033 reaction equation
[Cl:1][C:2]1[CH:16]=[CH:15][C:5]2[N:6]=[C:7]([N:9]3[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]3)[S:8][C:4]=2[CH:3]=1.[CH3:17][C:18]1[N:23]=[C:22]([S:24]([NH:27][C:28]2[CH:29]=[C:30]([CH:34]=[CH:35][CH:36]=2)[C:31](O)=[O:32])(=[O:26])=[O:25])[CH:21]=[CH:20][CH:19]=1>>[Cl:1][C:2]1[CH:16]=[CH:15][C:5]2[N:6]=[C:7]([N:9]3[CH2:14][CH2:13][N:12]([C:31]([C:30]4[CH:29]=[C:28]([NH:27][S:24]([C:22]5[CH:21]=[CH:20][CH:19]=[C:18]([CH3:17])[N:23]=5)(=[O:25])=[O:26])[CH:36]=[CH:35][CH:34]=4)=[O:32])[CH2:11][CH2:10]3)[S:8][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 27465956-Chloro-2-(piperazin-1-yl)-1,3-benzothiazoleHCID 679505863-(6-Methyl-pyridine-2-sulfonamido)benzoic acid

Product 1

HCID 67607460HCID 67607460, compound

Procedure

Compound 12 is prepared using synthesis method 2 using intermediates 3g and 5b (yield: 15%).

Sources & evidence

ORD record
ord-0de30e56cdcb434fb07039260db59d29
Source dataset
uspto-grants-2015_10
Patent number
US09156834B2

Reaction notes

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