HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86714384, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86714383 | HCID 86714383 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86714384 | HCID 86714384 | 97.3% |
Reaction Steps
32 mg of ((S)-2-{[1-(1-ethyl-propyl)-2-thiophen-2-ylmethyl-1H-benzoimidazole-5-carbonyl]-amino}-4-methyl-pentanoylamino)-acetic acid tert.-butyl ester were reacted with 0.8 ml of 4 M hydrochloric acid in dioxane at rt over night. The reaction mixture was then concentrated in vacuo to yield 28 mg (91%) of ((S)-2-{[1-(1-Ethyl-propyl)-2-thiophen-2-ylmethyl-1H-benzoimidazole-5-carbonyl]-amino}-4-methyl-pentanoylamino)-acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09156796B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-432938fd9e884efa9ec23982573db96e |
| Source note | uspto-grants-2015_10 |