HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl 4-fluoro-3-nitrobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 4-Fluoro-3-nitrobenzoic acid | HCID 67987 | — |
| Product | Methyl 4-fluoro-3-nitrobenzoate | HCID 5219721 | 90% |
Reaction Steps
5.55 g of 4-Fluoro-3-nitro-benzoic acid were dissolved in 50 ml of methanol, 6.4 ml of concentrated sulfuric acid were added and the reaction was heated to reflux for 3 h. The reaction was cooled, poured unto ice and the precipitated product was collected by suction and dried in vacuo. 5.40 g (90%) of 4-fluoro-3-nitro-benzoic acid methyl ester were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09156796B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-85d3cd4fa15849648a3406a9968d81cd |
| Source note | uspto-grants-2015_10 |