4-(1-Ethyl-propylamino)-3-nitro-benzoic acid methyl ester → Methyl 3-amino-4-(pentan-3-ylamino)benzoate

Beteiligte Stoffe

Reaktionsschritte

7.00 g of 4-(1-Ethyl-propylamino)-3-nitro-benzoic acid methyl ester were dissolved in 70 ml ethanol, 0.35 g of palladium on carbon (10%) were added and the mixture was hydrogenated at 5 bar for 4 h. The catalyst was removed by filtration over celite, the filtrate was concentrated and after crystallization from diethylether 5.00 g (65%) of 3-Amino-4-(1-ethyl-propylamino)-benzoic acid methyl ester were obtained.

Herkunft & Nachweise