4-(2-Methyl-cyclohexylamino)-3-nitro-benzoic acid methyl ester → 3-Amino-4-(2-methyl-cyclohexylamino)-benzoic acid methyl ester

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Reaction Steps

13.50 g 4-(2-Methyl-cyclohexylamino)-3-nitro-benzoic acid methyl ester were dissolved in 60 ml methanol, 0.49 g of palladium on carbon (10%) were added and the mixture was hydrogenated at 5 bar for 4 h. The catalyst was removed by filtration over celite, the filtrate was concentrated to obtain 12.00 g (99%) of 3-Amino-4-(2-methyl-cyclohexylamino)-benzoic acid methyl ester.

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