HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitro-4-(2-trifluoromethyl-cyclohexylamino)-benzoic acid methyl ester → HCID 86714449, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitro-4-(2-trifluoromethyl-cyclohexylamino)-benzoic acid methyl ester | HCID 86714448 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86714449 | HCID 86714449 | 97% |
Reaction Steps
1.63 g 3-Nitro-4-(2-trifluoromethyl-cyclohexylamino)-benzoic acid methyl ester were dissolved in 25 ml methanol, 0.03 g of palladium on carbon (10%) were added and the mixture was hydrogenated at 5 bar for 16 h. The catalyst was removed by filtration over celite, the filtrate was concentrated to obtain 1.44 g (97%) of 3-Amino-4-(2-trifluoromethyl-cyclohexylamino)-benzoic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09156796B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-eec625b33519442c8f260dde60b5deb7 |
| Source note | uspto-grants-2015_10 |