HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Ethyl-cyclohexylamino)-3-nitro-benzoic acid methyl ester → 3-Amino-4-(2-ethyl-cyclohexylamino)-benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Ethyl-cyclohexylamino)-3-nitro-benzoic acid methyl ester | HCID 86714455 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Amino-4-(2-ethyl-cyclohexylamino)-benzoic acid methyl ester | HCID 61468035 | 100% |
Reaction Steps
0.45 g 4-(2-Ethyl-cyclohexylamino)-3-nitro-benzoic acid methyl ester were dissolved in 60 ml methanol, 0.02 g of palladium on carbon (10%) were added and the mixture was hydrogenated at 5 bar for 4 h. The catalyst was removed by filtration over celite, the filtrate was concentrated to obtain 0.40 g (100%) of 3-Amino-4-(2-ethyl-cyclohexylamino)-benzoic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09156796B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-6296d352ad5c4c9b99656576ec1ce083 |
| Source note | uspto-grants-2015_10 |