HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86706943, compound → HCID 86706944, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86706943 | HCID 86706943 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 86706944 | HCID 86706944 | — |
Reaction Steps
A solution of 5-(1-methyl-1H-pyrazol-4-yl)-4-(morpholin-4-yl)-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine (C4) (200 mg, 0.48 mmol) in trifluoroacetic acid (5 mL) was stirred at room temperature for 2 hours. The reaction mixture was concentrated under reduced pressure to afford the product as a yellow oil, which was used for the next step without additional purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09156845B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-022e2ad23e8d48fc98dd22808b7eaa06 |
| Source note | uspto-grants-2015_10 |