Ethanamine, 2,2,2-trifluoro- → 2-{2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-1,3-thiazol-4-yl}-N-(2,2,2-trifluoroethyl)acetamide

Participants

Role	Name	HCID	Charge
Reactant	Ethanamine, 2,2,2-trifluoro-	HCID 9773	—
Reactant	2-(2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)acetic acid	HCID 86721182	—
Product	2-{2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-1,3-thiazol-4-yl}-N-(2,2,2-trifluoroethyl)acetamide	HCID 86721187	—

Reaction Steps

Using 2-(2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)acetic acid and 2,2,2-trifluoroethanamine and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09156837B2
Source dataset	uspto-grants-2015_10
ORD ID	ord-c2b57e567da64073aa92548f512de97c
Source note	uspto-grants-2015_10