2-(Oxan-4-yl)ethan-1-amine → 2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[2-(tetrahydro-2H-pyran-4-yl)ethyl]-1,3-thiazole-4-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	2-(Oxan-4-yl)ethan-1-amine	HCID 2773198	—
Reactant	2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazole-4-carboxylic acid	HCID 86721202	—
Product	2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[2-(tetrahydro-2H-pyran-4-yl)ethyl]-1,3-thiazole-4-carboxamide	HCID 86721207	—

Reaction Steps

Using 2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazole-4-carboxylic acid and 2-(tetrahydro-2H-pyran-4-yl)ethanamine and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09156837B2
Source dataset	uspto-grants-2015_10
ORD ID	ord-edf5a1e81f2140018e0708984d76295f
Source note	uspto-grants-2015_10