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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1750435Generated: October 27, 2026

Methyl iodide → ethyl 2-(2-(1-(tert-butyl)-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)propanoate

https://huagongshe.com/reaction/1750435

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactantethyl 2-(2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)acetateHCID 86721181—
Productethyl 2-(2-(1-(tert-butyl)-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)propanoateHCID 86721277—

Reaction Steps

Using ethyl 2-(2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)acetate and methyl iodide and by reaction and purification in the same manner as in the method described in Example 121, step 1, ethyl 2-(2-(1-(tert-butyl)-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)propanoate was obtained as a colorless oil

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09156837B2
Source datasetuspto-grants-2015_10
ORD IDord-e1ba3dc4cb2a418d95149c887fee7c18
Source noteuspto-grants-2015_10