Tetrahydropyran-4-ylacetic acid → HCID 71250794, compound

HRID 1750448Notes

Reaction equation

HRID 1750448 reaction equation
[C:1]([N:5]1[C:9]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)=[C:8]([C:17]2[S:18][CH:19]=[C:20]([CH2:22][NH2:23])[N:21]=2)[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2].[CH2:24]1[CH:29]([CH2:30][C:31](O)=[O:32])[CH2:28][CH2:27][O:26][CH2:25]1>>[C:1]([N:5]1[C:9]([C:10]2[CH:11]=[CH:12][C:13]([F:16])=[CH:14][CH:15]=2)=[C:8]([C:17]2[S:18][CH:19]=[C:20]([CH2:22][NH:23][C:31](=[O:32])[CH2:30][CH:29]3[CH2:28][CH2:27][O:26][CH2:25][CH2:24]3)[N:21]=2)[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 2773575Tetrahydropyran-4-ylacetic acidHCID 86721288HCID 86721288, compound

Product 1

HCID 71250794HCID 71250794, compound

Procedure

Using the compound obtained in step 2 and tetrahydropyranyl-4-acetic acid and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.

Workup

  1. customby reaction and purification in the same manner as in the method

Sources & evidence

ORD record
ord-8fef1faa75b945e8bc49655fd80b9457
Source dataset
uspto-grants-2015_10
Patent number
US09156837B2

Reaction notes

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