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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1750451Generated: October 30, 2026

2-(Oxan-4-yl)ethan-1-amine → 2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[2-(tetrahydro-2H-pyran-4-yl)ethyl]-4,5-dihydro-1,3-thiazole-4-carboxamide

https://huagongshe.com/reaction/1750451

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Oxan-4-yl)ethan-1-amineHCID 2773198—
Reactant2-(1-(tert-butyl)-5-(4-fluorophenyl)-1H-pyrazol-4-yl)-4,5-dihydrothiazole-4-carboxylic acidHCID 86721290—
Product2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[2-(tetrahydro-2H-pyran-4-yl)ethyl]-4,5-dihydro-1,3-thiazole-4-carboxamideHCID 71250797—

Reaction Steps

Using 2-(1-(tert-butyl)-5-(4-fluorophenyl)-1H-pyrazol-4-yl)-4,5-dihydrothiazole-4-carboxylic acid and 2-(tetrahydro-pyran-4-yl)-ethylamine and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09156837B2
Source datasetuspto-grants-2015_10
ORD IDord-f0e7b1b1a0564b3c8ef20e75ac77274d
Source noteuspto-grants-2015_10