HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Oxan-4-yl)ethan-1-amine → 2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[2-(tetrahydro-2H-pyran-4-yl)ethyl]-4,5-dihydro-1,3-thiazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Oxan-4-yl)ethan-1-amine | HCID 2773198 | — |
| Reactant | 2-(1-(tert-butyl)-5-(4-fluorophenyl)-1H-pyrazol-4-yl)-4,5-dihydrothiazole-4-carboxylic acid | HCID 86721290 | — |
| Product | 2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[2-(tetrahydro-2H-pyran-4-yl)ethyl]-4,5-dihydro-1,3-thiazole-4-carboxamide | HCID 71250797 | — |
Reaction Steps
Using 2-(1-(tert-butyl)-5-(4-fluorophenyl)-1H-pyrazol-4-yl)-4,5-dihydrothiazole-4-carboxylic acid and 2-(tetrahydro-pyran-4-yl)-ethylamine and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09156837B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-f0e7b1b1a0564b3c8ef20e75ac77274d |
| Source note | uspto-grants-2015_10 |