4-Aminoacetanilide → HCID 71250763, compound

HRID 1750455Notes

Reaction equation

HRID 1750455 reaction equation
[C:1]([N:5]1[C:9]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)=[C:8]([C:17]2[S:18][CH:19]=[C:20]([CH2:22][C:23](O)=[O:24])[N:21]=2)[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2].[CH3:26][C:27]([NH:29][C:30]1[CH:35]=[CH:34][C:33]([NH2:36])=[CH:32][CH:31]=1)=[O:28]>>[C:27]([NH:29][C:30]1[CH:35]=[CH:34][C:33]([NH:36][C:23](=[O:24])[CH2:22][C:20]2[N:21]=[C:17]([C:8]3[CH:7]=[N:6][N:5]([C:1]([CH3:3])([CH3:4])[CH3:2])[C:9]=3[C:10]3[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=3)[S:18][CH:19]=2)=[CH:32][CH:31]=1)(=[O:28])[CH3:26]

Participants

3

Reactant 2

HCID 312304-AminoacetanilideHCID 867211822-(2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)acetic acid

Product 1

HCID 71250763HCID 71250763, compound

Procedure

Using 2-(2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)acetic acid and 4-aminoacetanilide and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.

Workup

  1. customby reaction and purification in the same manner as in the method

Sources & evidence

ORD record
ord-e7d1e0dc86144a34bcc4e68081b57920
Source dataset
uspto-grants-2015_10
Patent number
US09156837B2

Reaction notes

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