[4-(Aminomethyl)oxan-4-yl]methanol → HCID 71250764, compound

HRID 1750458Notes

Reaction equation

HRID 1750458 reaction equation
[C:1]([N:5]1[C:9]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)=[C:8]([C:17]2[S:18][CH:19]=[C:20]([CH2:22][C:23]([OH:25])=O)[N:21]=2)[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2].[NH2:26][CH2:27][C:28]1([CH2:34][OH:35])[CH2:33][CH2:32][O:31][CH2:30][CH2:29]1>>[C:1]([N:5]1[C:9]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)=[C:8]([C:17]2[S:18][CH:19]=[C:20]([CH2:22][C:23]([NH:26][CH2:27][C:28]3([CH2:34][OH:35])[CH2:33][CH2:32][O:31][CH2:30][CH2:29]3)=[O:25])[N:21]=2)[CH:7]=[N:6]1)([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 22379474[4-(Aminomethyl)oxan-4-yl]methanolHCID 867211822-(2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)acetic acid

Product 1

HCID 71250764HCID 71250764, compound

Procedure

Using 2-(2-(1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl)thiazol-4-yl)acetic acid and [4-(aminomethyl)tetrahydro-2H-pyran-4-yl]methanol and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.

Workup

  1. customby reaction and purification in the same manner as in the method

Sources & evidence

ORD record
ord-ffb4b4e4004a46e299ecb597f422457c
Source dataset
uspto-grants-2015_10
Patent number
US09156837B2

Reaction notes

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