N-(2-Azido-2-methylcyclopentyl)-4-methylbenzene-1-sulfonamide → N-(2-Amino-2-methylcyclopentyl)-4-methylbenzene-1-sulfonamide

Participants

Reaction Steps

To a solution of N-(2-azido-2-methylcyclopentyl)-4-methylbenzene-1-sulfonamide (52.0 g, 176.87 mmol) in methanol (1100 ml) was added palladium on carbon (10% wt, 10.0 g). The reaction mixture was stirred at room temperature under a balloon of hydrogen gas for 12 hours. The reaction was filtered through diatomaceous earth (commercially sold under the trade mark “Celite”) and concentrated in vacuo to afford the title compound.

Provenance & Evidence