HRID1750600

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID9796

2,6-Difluorobenzoic acid

C7H4F2O2

结构：Cl.N[C@H]1CCC[C@@H]1Nc1cnc(C(F)(F)F)cn1

HCID118308118

未命名化合物

2 次

结构：O=C(N[C@H]1CCC[C@@H]1Nc1cnc(C(F)(F)F)cn1)c1ccccc1-n1cccn1

HCID118308230

未命名化合物

PRODUCTS

生成物

结构：O=C(N[C@H]1CCC[C@@H]1Nc1cnc(C(F)(F)F)cn1)c1c(F)cccc1F

HCID118308323

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure for 2-(1H-pyrazol-1-yl)-N-[(1S,2S)-2-{[5-(trifluoromethyl)pyrazin-2-yl]amino}cyclopentyl]benzamide (Example 31) from (1S,2S)-1-N-[5-(trifluoromethyl)pyrazin-2-yl]cyclopentane-1,2-diamine hydrochloride (Intermediate 14, 213 mg, 0.75 mmol) and 2,6-difluorobenzoic acid (CAS number 385-00-2; 131 mg, 0.83 mmol) to afford the title compound.

WORKUP

后处理

customPrepared