HRID1750630

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID68685145

3-Cyclopropylpyridine-2-carboxylic acid

C9H9NO2

2 次

结构：Cl.N[C@H]1CCC[C@@H]1Nc1cnc(C(F)(F)F)cn1

HCID118308118

未命名化合物

2 次

结构：O=C(N[C@H]1CCC[C@@H]1Nc1cnc(C(F)(F)F)cn1)c1ccccc1C(F)(F)F

HCID118308264

未命名化合物

PRODUCTS

生成物

结构：O=C(N[C@H]1CCC[C@@H]1Nc1cnc(C(F)(F)F)cn1)c1ncccc1C1CC1

HCID118308193

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure for 2-(trifluoromethyl)-N-[(1S,2S)-2-{[5-(trifluoromethyl)pyrazin-2-yl]amino}cyclopentyl]benzamide (Example 62) from (1S,2S)-1-N-[5-(trifluoromethyl)pyrazin-2-yl]cyclopentane-1,2-diamine hydrochloride (Intermediate 14; 75 mg, 0.30 mmol) and 3-cyclopropylpyridine-2-carboxylic acid (Intermediate 16; 50 mg, 0.31 mmol) to afford the title compound.

WORKUP

后处理

customPrepared