HRID1750686

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66742288

未命名化合物

结构：O=C(N[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)cc1Cl)c1ncccc1-n1nccn1

HCID118308168

未命名化合物

结构：Cl.N[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)cc1F

HCID118308208

未命名化合物

2 次

PRODUCTS

生成物

结构：O=C(N[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)cc1F)c1ncccc1-n1nccn1

HCID118308221

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure for N-[(1S,2S)-2-{ [3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}cyclopentyl]-3-(2H-1,2,3-triazol-2-yl)pyridine-2-carboxamide (Example 122) from (1S,2S)-1-N-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]cyclopentane-1,2-diamine hydrochloride (Intermediate 34; 100 mg, 0.33 mmol) and 3-(2H-1,2,3-triazol-2-yl)pyridine-2-carboxylic acid (CAS number 1252907-86-0; 66 mg, 0.35 mmol) to afford the title compound.

WORKUP

后处理

customPrepared