HRID1750710

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID19802118

未命名化合物

结构：CCc1nc(C(F)(F)F)cnc1N[C@H]1CCC[C@@H]1NC(=O)c1ccccc1-c1nc(C)no1

HCID118308090

未命名化合物

结构：CCc1nc(C(F)(F)F)cnc1N[C@H]1CCC[C@@H]1N.Cl

HCID118308132

未命名化合物

2 次

PRODUCTS

生成物

结构：CCc1nc(C(F)(F)F)cnc1N[C@H]1CCC[C@@H]1NC(=O)c1ccccc1-c1ncccn1

HCID118308318

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure for N-[(1S,2S)-2-{[3-ethyl-5-(trifluoromethyl)pyrazin-2-yl]amino}cyclopentyl]-2-(3-methyl-1,2,4-oxadiazol-5-yl)benzamide (Example 149) from (1S,2S)-1-N-[3-ethyl-5-(trifluoromethyl)pyrazin-2-yl]cyclopentane-1,2-diamine hydrochloride (Intermediate 41; 450 mg 1.64 mmol) and 2-(pyrimidin-2-yl)benzoic acid (CAS number 400892-62-8; 328 mg, 1.64 mmol) to afford the title compound.

WORKUP

后处理

customPrepared