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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1750949Generated: October 31, 2026

Hydrochloric Acid → HCID 66652211, compound

https://huagongshe.com/reaction/1750949

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58046642HCID 58046642—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652211HCID 66652211—

Reaction Steps

To (S)-tert-butyl 3-(3-(sec-butoxycarbonyl)benzyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.072 g, 0.14 mmol) was added 4M solution of HCl in dioxane (1.5 mL). After stirring at room temperature for an hour, the reaction mixture was concentrated in vacuo to obtain (S)-sec-butyl 3-((4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate as a hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09156840B2
Source datasetuspto-grants-2015_10
ORD IDord-2adb5a227a134e3f802b7a60ec09c787
Source noteuspto-grants-2015_10