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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1751005Generated: October 28, 2026

Hydrochloric Acid → HCID 66652119, compound

https://huagongshe.com/reaction/1751005

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58046760HCID 58046760—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652119HCID 66652119—

Reaction Steps

To tert-butyl 3-(3-(methoxycarbonyl)benzyl)-1-(4-methoxyphenyl)-4-oxo-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.47 g, 0.92 mmol) was added 4M solution of HCl in dioxane (10 mL). After stirring at room temperature for 2 hours, the reaction mixture was concentrated in vacuo to obtain methyl 3-((1-(4-methoxyphenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate as a hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09156840B2
Source datasetuspto-grants-2015_10
ORD IDord-28facb5cc91a49eb89a2f5b64c419e29
Source noteuspto-grants-2015_10