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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1751141Generated: October 28, 2026

Hydrochloric Acid → HCID 66652365, compound

https://huagongshe.com/reaction/1751141

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 66652102HCID 66652102—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652365HCID 66652365—

Reaction Steps

To tert-butyl 3-(4-(methylsulfonamido)phenyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.91 g, 1.82 mmol) was added 4M solution of HCl in dioxane (10 mL). After stirring at room temperature for 18 hours, the reaction mixture was concentrated in vacuo to obtain N-(4-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)phenyl)methanesulfonamide as a hydrochloride salt (0.7 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09156840B2
Source datasetuspto-grants-2015_10
ORD IDord-99f7a72fc98d45e19689fbdf4c871eab
Source noteuspto-grants-2015_10