HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 66652365, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 66652102 | HCID 66652102 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 66652365 | HCID 66652365 | — |
Reaction Steps
To tert-butyl 3-(4-(methylsulfonamido)phenyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.91 g, 1.82 mmol) was added 4M solution of HCl in dioxane (10 mL). After stirring at room temperature for 18 hours, the reaction mixture was concentrated in vacuo to obtain N-(4-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)phenyl)methanesulfonamide as a hydrochloride salt (0.7 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09156840B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-99f7a72fc98d45e19689fbdf4c871eab |
| Source note | uspto-grants-2015_10 |