Hydrazine, 1,1-diphenyl-, hydrochloride (1:1) → HCID 86762609, compound

HRID 1751158Notes

Reaction equation

HRID 1751158 reaction equation
Cl.[C:2]1([N:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)N)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:16][CH:17]([C:26](=O)[CH3:27])[CH2:18][CH2:19][CH2:20][CH2:21][S:22]([OH:25])(=[O:24])=[O:23]>C(O)(=O)C>[CH3:27][C:26]1[C:17]([CH3:16])([CH2:18][CH2:19][CH2:20][CH2:21][S:22]([O-:25])(=[O:24])=[O:23])[C:7]2[C:2](=[CH:3][CH:4]=[CH:5][CH:6]=2)[N+:8]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 10738Hydrazine, 1,1-diphenyl-, hydrochloride (1:1)HCID 579033515-Methyl-6-oxoheptanesulfonic acid

Product 1

HCID 86762609HCID 86762609, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

N,N-Diphenylhydrazine hydrochloride (0.01 mol, 2.2 g), 5-methyl-6-oxoheptanesulfonic acid (0.017 mol, 3.0 g) in glacial acetic acid (20 ml) were stirred at room temperature (˜20° C.) for an hour then at 100° C. for 3 hours (TLC check). The reaction mixture was cooled down and the solvent removed under vacuum. The residue was washed with diethyl ether and purified by flash column on silicagel. Yield: 2 g (56%). Structure confirmed by NMR spectrum.

Workup

  1. temperatureThe reaction mixture was cooled down
  2. customthe solvent removed under vacuum
  3. washThe residue was washed with diethyl ether
  4. custompurified by flash column on silicagel

Sources & evidence

ORD record
ord-240538d8ccc04c7d9339f090ac16795a
Source dataset
uspto-grants-2015_10
Patent number
US09156987B2

Reaction notes

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