反应详情

温度

30 °C

Into a NaOH aqueous solution (3.46 g, 24.0 mL) for hydrolysis, 10.4 g (72.0 mmol) of ethyl 2-methylacetoacetate was added, and stirred under heating at 30° C. for 3 hours. After the three hours, the reaction mixture was cooled down to 0° C., and a 5 N HNO3 aqueous solution was added thereto to make the reaction liquid acidic. To the reaction mixture, 4.34 g (7.20 mmol) of copper (II) nitrate aqueous solution was added dropwise, and subjected to magnetic stirring for 3 hours. The precipitated solid was taken out by filtration, and washed with ion-exchanged water and acetone to obtain 2.81 g (8.52 mmol) of copper (II) 2-methylacetoacetate dihydrate in the form of blue solid.

1. additionwas added
2. temperatureAfter the three hours, the reaction mixture was cooled down to 0° C.
3. customthe reaction liquid acidic
4. stirringto magnetic stirring for 3 hours
5. filtrationThe precipitated solid was taken out by filtration
6. washwashed with ion-exchanged water and acetone