Acetic Anhydride → HCID 86612010, compound

HRID 1751312Notes

Reaction equation

[O:1]1[CH2:6][CH2:5][N:4]([CH2:7][CH:8]([OH:23])[CH2:9][C:10]([F:22])([F:21])[C:11]([F:20])([F:19])[C:12]([F:18])([F:17])[C:13]([F:16])([F:15])[F:14])[CH2:3][CH2:2]1.[C:24](OC(=O)C)(=[O:26])[CH3:25]>>[C:24]([O:23][CH:8]([CH2:9][C:10]([F:21])([F:22])[C:11]([F:19])([F:20])[C:12]([F:17])([F:18])[C:13]([F:16])([F:14])[F:15])[CH2:7][N:4]1[CH2:5][CH2:6][O:1][CH2:2][CH2:3]1)(=[O:26])[CH3:25]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 86612009HCID 86612009, compound

Product 1

HCID 86612010HCID 86612010, compoundYield 95.1%

Conditions

Temperature: 50 °C

Procedure

To 36.3 g of 1-morpholino-4,4,5,5,6,6,7,7,7-nonafluoro-2-heptanol was added 11.2 g of acetic anhydride. The mixture was stirred at 50° C. for 10 hours. This was followed by conventional aqueous work-up and purification by silica gel column chromatography. There was obtained 38.5 g of 1-morpholino-4,4,5,5,6,6,7,7,7-nonafluoro-2-heptyl acetate (yield 95%).

Workup

customThis was followed by conventional aqueous work-up and purification by silica gel column chromatography

Sources & evidence

ORD record: ord-f2caa759676a4cbf877821bcffea15a4
Source dataset: uspto-grants-2015_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09158191B2

Reaction notes

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