Acetic acid 10-acetoxymethyl-anthracen-9-ylmethyl ester → HCID 87731579, compound

HRID 1751314Notes

Reaction equation

HRID 1751314 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][O:9][CH2:10][CH:11]([OH:26])[CH2:12][C:13]([F:25])([F:24])[C:14]([F:23])([F:22])[C:15]([F:21])([F:20])[C:16]([F:19])([F:18])[F:17])[CH2:3][CH2:2]1.[CH3:27][C:28](OCC1C2C(=CC=CC=2)C(COC(C)=O)=C2C=1C=CC=C2)=[O:29]>>[C:28]([O:26][CH:11]([CH2:12][C:13]([F:24])([F:25])[C:14]([F:22])([F:23])[C:15]([F:21])([F:20])[C:16]([F:19])([F:17])[F:18])[CH2:10][O:9][CH2:8][CH2:7][N:4]1[CH2:5][CH2:6][O:1][CH2:2][CH2:3]1)(=[O:29])[CH3:27]

Participants

3

Reactant 2

HCID 613145Acetic acid 10-acetoxymethyl-anthracen-9-ylmethyl esterHCID 86612011HCID 86612011, compound

Product 1

HCID 87731579HCID 87731579, compoundYield 273.5%

Conditions

Temperature
50 °C

Procedure

To 40.7 g of 1-(2-morpholinoethoxy)-4,4,5,5,6,6,7,7,7-nonafluoro-2-heptanol was added 11.2 g of acetic anhyride. The mixture was stirred at 50° C. for 10 hours, followed by conventional aqueous work-up and purification by silica gel column chromatography. There was obtained 42.7 g of 1-(2-morpholinoethoxy)-4,4,5,5,6,6,7,7,7-nonafluoro-2-heptyl acetate (yield 95%).

Workup

  1. customfollowed by conventional aqueous work-up and purification by silica gel column chromatography

Sources & evidence

ORD record
ord-06d1210517964487b3fd3ba28e74cf15
Source dataset
uspto-grants-2015_10
Patent number
US09158191B2

Reaction notes

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