2-Amino-2-phenylpropanoic acid → 2-Methoxycarbonylamino-2-phenyl-propionic acid

HRID 1751517Notes

Reaction equation

HRID 1751517 reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([NH:12][C:13]([O:15][CH3:16])=[O:14])[C:9]([OH:11])=[O:10].N[C:18](C1C=CC=CC=1)(C)C(O)=O>>[CH3:16][O:15][C:13]([NH:12][C:8]([C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:2]=1)([CH3:18])[C:9]([OH:11])=[O:10])=[O:14]

Participants

3

Reactant 2

HCID 317222-Amino-2-phenylpropanoic acidHCID 69672259HCID 69672259, compound

Product 1

HCID 624897412-Methoxycarbonylamino-2-phenyl-propionic acid

Procedure

2-Methoxycarbonylamino-2-phenyl-propionic acid was prepared using the procedure used to prepare (2-Fluoro-phenyl)-methoxycarbonylamino-acetic acid using 2-Amino-2-phenyl-propionic acid. LCMS-ESI+: calc'd for C11H13NO4: 223.08 (M+); Found: 223.96 (M+H+)

Sources & evidence

ORD record
ord-adf1f195875143e3807438ad8f52af34
Source dataset
uspto-grants-2015_10
Patent number
US09156823B2

Reaction notes

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